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ÀÔ·ÂÀÏÀÚ: 2015-02-14
À¯È¿ÀÏÀÚ: 61825-94-3

Á¦¸ñ: Oxaliplatin
  »óÇ°ºÐ·ù: È­Çкñ·á¿Í ³ó¾à
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  ³»¿ë: Oxaliplatin Synonyms: [SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM;OXALIPLATIN;trans-l-diaminocyclohexane oxalatoplatinum;(1,2-cyclohexanediamine-n,n¡¯)(ethanedioato(2-)-o,o¡¯)-platinu(sp-4-2-(1r-tr;1-ohp;oxalato(1r,2r-cyclohexanediammine)platinum(ii);oxalatoplatin;oxalatoplatinum CAS: 61825-94-3 MF: C8H14N2O4Pt MW: 397.29 EINECS: 274-613-9 Chemical Properties White Crystalline Solid Usage Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic. Usage vasodilator Usage A antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA Biological Activity Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (cis-Diaminodichloroplatinum ) and shows antitumor activity in cell lines with acquired cisplatin resistance.

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