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3,4,5-Trimethoxycinnamic acid |
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3,4,5-Trimethoxycinnamic acid:Traditional Chinese medicine in the treatment of depression
Depression is a syndrome that the main feature is the person who has the low mood which is significant and persistent ,the main syndrome is :low mood,slow thinking reaction,Volitional activity drops,Loss of appetite, Insomnia asthenia,atc. As the aggravate that the society competes, a lot of emergency factors increase, depression has become a high incidence trend year by year. At present, depression ranked fourth in the world¡¯s disabling disease, it will become the biggest disease second only to heart disease. In China, there are more than 26 million people suffering from depression, it brings the total economic burden of China reached 62.2billion yuan.
The etiology of depression has not been completely elucidated, but most people think that the cerebral monoamine neurotransmitters related to inadequate, currently in clinical use of antidepressant drugs more developed. These drugs have a certain effect, but there are side effects of large, expensive, drug dependence, poor quality of life. Therefore, traditional Chinese medicine in antidepressant treatment potential, is being excavated.
Attending feel abnormal characteristics especially foreign body sensation in the throat of Banxia Houpu Decoction with releasing stagnation, phlegm effect. The researchers found that, the formula of Perilla frutescens with 3, 4, 5 -Trimethoxy cinnamic acid, has good antidepressant effects. The experiment proves, perilla of Apiin yuan and 3, 4, 5 - Trimethoxy cinnamic acids, can weaken the forced swimming in mice induced by dopamine transformation reduces the amygdala, hypothalamus in dopamine increased transformation function, thus to some extent on depression effect. The researchers said, perilla plus 3, 4, 5 - Trimethoxy cinnamic acid shows the good development prospects of Chinese traditional medicine in resisting depression.
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3,4,5-Trimethoxycinnamic acid£ºTraditional Chinese medicine in the treatment of depression
Depression is a syndrome that the main feature is the person who has the low mood which is significant and persistent ,the main syndrome is :low mood,slow thinking reaction,Volitional activity drops,Loss of appetite, Insomnia asthenia,atc. As the aggravate that the society competes, a lot of emergency factors increase, depression has become a high incidence trend year by year. At present, depression ranked fourth in the world¡¯s disabling disease, it will become the biggest disease second only to heart disease. In China, there are more than 26 million people suffering from depression, it brings the total economic burden of China reached 62.2billion yuan.
The etiology of depression has not been completely elucidated, but most people think that the cerebral monoamine neurotransmitters related to inadequate, currently in clinical use of antidepressant drugs more developed. These drugs have a certain effect, but there are side effects of large, expensive, drug dependence, poor quality of life. Therefore, traditional Chinese medicine in antidepressant treatment potential, is being excavated.
Attending feel abnormal characteristics especially foreign body sensation in the throat of Banxia Houpu Decoction with releasing stagnation, phlegm effect. The researchers found that, the formula of Perilla frutescens with 3, 4, 5 -Trimethoxy cinnamic acid, has good antidepressant effects. The experiment proves, perilla of Apiin yuan and 3, 4, 5 - Trimethoxy cinnamic acids, can weaken the forced swimming in mice induced by dopamine transformation reduces the amygdala, hypothalamus in dopamine increased transformation function, thus to some extent on depression effect. The researchers said, perilla plus 3, 4, 5 - Trimethoxy cinnamic acid shows the good development prospects of Chinese traditional medicine in resisting depression.
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