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제 목:
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Troxerutin |
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상품분류: |
유기화학원료와 중간체
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등록분류: |
Offer to Sell |
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내용: |
Additional_detail: Troxerutin, a trihydroxy-ethyl-
rutoside, in the venous wall have
been studied in patients
undergoing long saphenous vein
surgery. Troxerutin, an
autofluorescent drug, is
currently used to relieve oedema
and subjective symptoms in
patients with chronic venous
insufficiency. In order to
determine the localization of the
troxerutin, a confocal scanning
laser microscope has been used to
record the fluorescence from vein
cross sections. The quantified
fluorescence was used as a
measure of the local
concentration of troxerutin. In
order to reduce the effects of
local variation, several images
have been scanned from each
specimen. Then the recorded data
have been analysed to see how the
fluorescence varies in the radial
direction within the venous wall.
Results showed that troxerutin
was significantly accumulated in
both inner and outer parts of the
venous wall. Whereas inner wall
troxerutin uptake resulted from
direct diffusion through the
lumen, the outer wall uptake
proceeded likely from the vasa
vasorum circulation.
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