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ÀÔ·ÂÀÏÀÚ: 2015-01-08
À¯È¿ÀÏÀÚ: 126-07-8

Á¦¸ñ: (+)-Griseofulvin
  »óǰºÐ·ù: È­Çкñ·á¿Í ³ó¾à
  µî·ÏºÐ·ù: Offer to Sell
  ³»¿ë: (+)-Griseofulvin Synonyms: (+)-GRISEOFULVIN;GRISEOFULVIN;[2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE;(2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-DIONE;7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYL-, (1'S-TRANS)-SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE;(+)-griseofulvi;(2s-trans)-7-chloro-2¡¯,4,6-trimethoxy-6¡¯-methylspiro[benzofuran-2(3h),1¡¯-[2]cy;(2s-trans)-xy-6¡¯-methyl CAS: 126-07-8 MF: C17H17ClO6 MW: 352.77 EINECS: 204-767-4 Chemical Properties Crystalline Solid Usage adrenegic blocker, Ca channel blocker, coronary vasodilator, antiarrhythmic Usage antifungal, inhibits mitosis in metaphase Usage Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy. Usage It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum

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