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2015-01-31 |
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85-41-6 |
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O-Phthalimide |
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Offer to Sell |
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O-Phthalimide
Synonyms: LABOTEST-BB LTBB000782;ISOINDOLE-1,3-DIONE;1,2-PHTHALIC IMIDE;1,2-BENZENEDICARBOXIMIDE;1,3-DIHYDROISOINDOLE-1,3-DIONE;1,3-ISOINDOLEDIONE;1H-ISOINDOLE-1,3(2H)-DIONE;O-PHTHALIC IMIDE
CAS: 85-41-6
MF: C8H5NO2
MW: 147.13
EINECS: 201-603-3
Chemical Properties white to slightly yellowish crystalline flakes
Usage Phthalimide is a reagent used to transform allyl- and alkyl halides into protected primary amines. Phthalimide analogues have been extensively used in medicinal chemistry owing to their wide spectrum of applications as anti-convulsant, anti-inflammatory, analgesic, hypolipidimic and immunomodulatory activities.
General Description White to light tan powder. Slightly acidic.
Air & Water Reactions Insoluble in water.
Reactivity Profile O-Phthalimide is an imide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). O-Phthalimide forms salts with bases.
Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition O-Phthalimide emits toxic fumes of nitrogen oxides.
Fire Hazard Literature sources indicate that O-Phthalimide is combustible. |
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