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ÀÔ·ÂÀÏÀÚ: 2015-02-10
À¯È¿ÀÏÀÚ: 71675-85-9

Á¦¸ñ: Amisulpride
  »óǰºÐ·ù: È­Çкñ·á¿Í ³ó¾à
  µî·ÏºÐ·ù: Offer to Sell
  ³»¿ë: Amisulpride Synonyms: 4-AMINO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-5-(ETHYLSULFONYL)-2-METHOXYBENZAMIDE;AMISULPRIDE;AMINOSULTOPRIDE;DAN-2163;DENIBAN;SOCIAN;SOLIAN;4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzam CAS: 71675-85-9 MF: C17H27N3O4S MW: 369.48 EINECS: 275-831-7 Chemical Properties Off-White Solid Usage Neuroleptic agent, an analogue of sulpiride. Used as an antipsychotic. Dopamine receptor antagonist Usage Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist. Biological Activity Potent, selective dopamine D 2 and D 3 receptor antagonist. K i values are 2.8 and 3.2 nM respectively for human D 2 and D 3 and > 1000 nM for human D 1 , D 4 and D 5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D 2 /D 3 receptors at higher doses. Preferentially interacts with limbic D 2 -like receptors in vivo . Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride.

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