 오퍼게시판 |
|
|
| 입력일자: |
2015-02-10 |
| 유효일자: |
152520-56-4 |
제 목:
|
Nebivolol hydrochloride |
|
상품분류: |
화학비료와 농약 |
|
등록분류: |
Offer to Sell |
|
내용: |
Nebivolol hydrochloride
Synonyms: RAC NEBIVOLOL, HYDROCHLORIDE;a,a(Iminodimethylene)bis[6-fluoro-2-chromanmethanol] Hydrochloride;Lobivon;Nebilet;Nebilox;R-67555;NEBIVOLOLHYDROCHLORIDE(SUBJECTTOPATENTFREE);a,a'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol hydrochloride
CAS: 152520-56-4
MF: C22H26ClF2NO4
MW: 441.9
Chemical Properties White to Off-White Powder
Usage A ?-Adrenergic blocker. Used as an antihypertensive
Usage Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM
Biological Activity Highly selective β 1 -adrenoceptor antagonist (K i values are 0.88, 20, 44, 700, 1160, 2400 and 4000 nM at β 1 , 5-HT 1A , β 2 , 5-HT 2 , α 1 , H 1 and D 2 receptors respectively). Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism (EC 50 = 11.36 μ M in renal arteries) and displays antihypertensive activity in vivo . |
연락처 |
| 담
당 자: |
Ivy Young |
| 회사주소: |
No 496 Zhongshan Road, Wuhan City, Hubei Province, China 430064 |
| 우편번호: |
430064 |
| 전화번호: |
86-027-50755963 |
| 팩스번호:
|
86-027-50755963 |
| E - mail: |
ycwlb045@yccreate.com |
|
현재위치
: Home > Trade 
