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ÀÔ·ÂÀÏÀÚ: 2015-02-10
À¯È¿ÀÏÀÚ: 85650-52-8

Á¦¸ñ: Mirtazapine
  »óǰºÐ·ù: È­Çкñ·á¿Í ³ó¾à
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  ³»¿ë: Mirtazapine Synonyms: 1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO[2,1-A]PYRIDO[2,3-C][2]BENZAZEPINE;(rs)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino-[2,1-a]pyrido[2,3-c][2]benzazepine;REMERON;ORG-3770;MIRTAZANINE;MIRTAZAPINE;MIRTAZEPINE;ZISPIN CAS: 85650-52-8 MF: C17H19N3 MW: 265.35 EINECS: 288-060-6 Chemical Properties White Solid Usage Mirtazapine (Remeron, Avanza) is a potent tetracyclic antidepressant. Mirtazapine (Remeron, Avanza) used primarily in the treatment of depression. It is also sometimes used as a hypnotic, antiemetic, and appetite stimulant, and for the treatment of anxiet Usage An ¥á2-Adrenergic blocker; analogue of Mianserin. Antidepressant. Biological Activity Antidepressant agent; potent 5-HT 2 , 5-HT 3 and histamine H 1 receptor antagonist and moderately potent ¥á 2 -adrenoceptor antagonist (pK i values are 8.05, ~ 8.1, 9.3 and 6.95 respectively). Enhances noradrenalin (NA) release in rat brain via inhibition of ¥á 2 -adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pK i values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo .

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