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2015-02-10 |
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85650-52-8 |
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Mirtazapine |
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Offer to Sell |
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Mirtazapine
Synonyms: 1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO[2,1-A]PYRIDO[2,3-C][2]BENZAZEPINE;(rs)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino-[2,1-a]pyrido[2,3-c][2]benzazepine;REMERON;ORG-3770;MIRTAZANINE;MIRTAZAPINE;MIRTAZEPINE;ZISPIN
CAS: 85650-52-8
MF: C17H19N3
MW: 265.35
EINECS: 288-060-6
Chemical Properties White Solid
Usage Mirtazapine (Remeron, Avanza) is a potent tetracyclic antidepressant. Mirtazapine (Remeron, Avanza) used primarily in the treatment of depression. It is also sometimes used as a hypnotic, antiemetic, and appetite stimulant, and for the treatment of anxiet
Usage An ¥á2-Adrenergic blocker; analogue of Mianserin. Antidepressant.
Biological Activity Antidepressant agent; potent 5-HT 2 , 5-HT 3 and histamine H 1 receptor antagonist and moderately potent ¥á 2 -adrenoceptor antagonist (pK i values are 8.05, ~ 8.1, 9.3 and 6.95 respectively). Enhances noradrenalin (NA) release in rat brain via inhibition of ¥á 2 -adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pK i values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo . |
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86-027-50755963 |
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