 오퍼게시판 |
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| 입력일자: |
2015-02-10 |
| 유효일자: |
94055-76-2 |
제 목:
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Suplatast tosilate |
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상품분류: |
화학비료와 농약 |
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등록분류: |
Offer to Sell |
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내용: |
Suplatast tosilate
Synonyms: (2-(4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl)ethyl)dimethylsulfonium p-toluenesulfonate;SUPLATAST TOSILATE;Suplatast tosylate;Suplatast;2-[4-(2-Hydroxy-3-ethoxypropoxy)phenylcarbamoyl]ethyldimethylsulfonium·4-methylbenzenesulfonate;IPD-1151T;S,S-Dimethyl-3-oxo-3-[4-(2-hydroxy-3-ethoxypropoxy)anilino]propane-1-sulfonium·4-methylbenzenesulfonate;[2-[[[4-(2-Hydroxy-3-ethoxypropoxy)phenyl]amino]carbonyl]ethyl]dimethylsulfonium
CAS: 94055-76-2
MF: C23H33NO7S2
MW: 499.64062
Usage Suplatast Tosylate is an antiallergic drug. Suplatast Tosylate inhibits antigen-induced histamine release from mast cells as well as IgE antibody formation. Suplatast Tosylate suppresses interleukin (IL)-4 release from T cells, however in human peripheral basophils, Suplatast Tosylate inhibited the antigen-induced release of IL-13 but not IL-4.
Usage Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.
Biological Activity Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN- γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active. |
연락처 |
| 담
당 자: |
Ivy Young |
| 회사주소: |
No 496 Zhongshan Road, Wuhan City, Hubei Province, China 430064 |
| 우편번호: |
430064 |
| 전화번호: |
86-027-50755963 |
| 팩스번호:
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86-027-50755963 |
| E - mail: |
ycwlb045@yccreate.com |
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