 오퍼게시판 |
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| 입력일자: |
2015-02-10 |
| 유효일자: |
184475-35-2 |
제 목:
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Gefitinib |
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상품분류: |
화학비료와 농약 |
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등록분류: |
Offer to Sell |
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내용: |
Gefitinib
Synonyms: IRESSA;GEFITINIB;AKOS 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;ZD 1839;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-;Gefitinib(TINIBS)
CAS: 184475-35-2
MF: C22H24ClFN4O3
MW: 446.9
Chemical Properties Light-Yellow Crystalline Powder
Usage Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.
Usage Gefitinib is an antineoplastic.
Biological Activity Orally active, selective inhibitor of EGFR tyrosine kinase (IC 50 = 23-79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts. |
연락처 |
| 담
당 자: |
Ivy Young |
| 회사주소: |
No 496 Zhongshan Road, Wuhan City, Hubei Province, China 430064 |
| 우편번호: |
430064 |
| 전화번호: |
86-027-50755963 |
| 팩스번호:
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86-027-50755963 |
| E - mail: |
ycwlb045@yccreate.com |
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