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2015-02-10 |
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21679-14-1 |
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Fludarabine |
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Offer to Sell |
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Fludarabine
Synonyms: 2-Fluoroadeninearabinoside;9-beta-d-arabinofuranosyl-2-fluoro-9h-purin-6-amin;9-beta-d-arabinofuranosyl-2-fluoro-adenin;f-ara-a;6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE;9-bata-d-arabinofuranosyl-2-fluoroadenine;9-BETA-D-ARABINOFURANOSYL-2-FLUORO-9H-PURIN-6-AMINE;9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE
CAS: 21679-14-1
MF: C10H12FN5O4
MW: 285.23
EINECS: 244-525-5
Chemical Properties White Solid
Usage Used as an antineoplastic
Usage A STAT-1 activation inhibitor and a DNA synthesis inhibitor.?
Usage phosphate as antineoplastic;inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase
Usage Irreversible muscarinic agonist
Usage DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription
Biological Activity Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 ¥ì M in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Displays anticancer activity against hematological malignancies in vivo . |
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Ivy Young |
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No 496 Zhongshan Road, Wuhan City, Hubei Province, China 430064 |
¿ìÆí¹øÈ£: |
430064 |
ÀüȹøÈ£: |
86-027-50755963 |
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86-027-50755963 |
E - mail: |
ycwlb045@yccreate.com |
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