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ÀÔ·ÂÀÏÀÚ: 2015-02-11
À¯È¿ÀÏÀÚ: 106685-40-9

Á¦¸ñ: Adapalene
  »óÇ°ºÐ·ù: È­Çкñ·á¿Í ³ó¾à
  µî·ÏºÐ·ù: Offer to Sell
  ³»¿ë: Adapalene Synonyms: ADAPALENE;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHALENE CARBOXYLIC ACID;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;6-[3-(1-adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid;Adapalen;6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid;CD-271;Differi CAS: 106685-40-9 MF: C28H28O3 MW: 412.52 Chemical Properties White Crystalline Solid Usage Retinoid selective for retinoic acid receptor (RAR) subtypes ?and . Antiacne Usage Retinoid selective for retinoic acid receptor (RAR) subtypes ¥â and ¥ã. Antiacne. Usage anesthetic Usage inhibits serotonin and noradrenaline reuptake antidepressant antimigraine therapeutic Biological Activity Retinoic acid analog that is a RAR ¥â and RAR ¥ã agonist (AC 50 values are 2.2, 9.3, 22 and > 1000 nM for RAR ¥â , RAR ¥ã , RAR ¥á and RXR ¥á receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cell in vitro . Displays comedolytic activity.

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