 오퍼게시판 |
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| 입력일자: |
2015-02-13 |
| 유효일자: |
138112-76-2 |
제 목:
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AGOMELATINE |
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상품분류: |
화학비료와 농약 |
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등록분류: |
Offer to Sell |
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내용: |
AGOMELATINE
Synonyms: AGOMELATINE;n-(2-(7-methoxy-1-naphthalenyl)ethyl)-acetamid;n-(2-(7-methoxy-1-naphthalenyl)ethyl)acetamide;n-(2-(7-methoxynaphth-1-yl)ethyl)acetamide;S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide;S 20098;AGOMELATIN;Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-
CAS: 138112-76-2
MF: C15H17NO2
MW: 243.30098
Chemical Properties White Solid
Usage Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of
Usage Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. |
연락처 |
| 담
당 자: |
Ivy Young |
| 회사주소: |
No 496 Zhongshan Road, Wuhan City, Hubei Province, China 430064 |
| 우편번호: |
430064 |
| 전화번호: |
86-027-50755963 |
| 팩스번호:
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86-027-50755963 |
| E - mail: |
ycwlb045@yccreate.com |
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