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2015-02-14 |
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61825-94-3 |
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Oxaliplatin |
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Offer to Sell |
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Oxaliplatin
Synonyms: [SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM;OXALIPLATIN;trans-l-diaminocyclohexane oxalatoplatinum;(1,2-cyclohexanediamine-n,n¡¯)(ethanedioato(2-)-o,o¡¯)-platinu(sp-4-2-(1r-tr;1-ohp;oxalato(1r,2r-cyclohexanediammine)platinum(ii);oxalatoplatin;oxalatoplatinum
CAS: 61825-94-3
MF: C8H14N2O4Pt
MW: 397.29
EINECS: 274-613-9
Chemical Properties White Crystalline Solid
Usage Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
Usage vasodilator
Usage A antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA
Biological Activity Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (cis-Diaminodichloroplatinum ) and shows antitumor activity in cell lines with acquired cisplatin resistance. |
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Ivy Young |
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No 496 Zhongshan Road, Wuhan City, Hubei Province, China 430064 |
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430064 |
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86-027-50755963 |
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86-027-50755963 |
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