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ÀÔ·ÂÀÏÀÚ: 2015-02-14
À¯È¿ÀÏÀÚ: 15318-45-3

Á¦¸ñ: Thiamphenicol
  »óÇ°ºÐ·ù: È­Çкñ·á¿Í ³ó¾à
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  ³»¿ë: Thiamphenicol Synonyms: THIAMPHENICOL;methylsulfonyl chloramphenicol;D-THREO-2,2-DICHLORO-N-(BETA-HYDROXY-ALPHA-[HYDROXYMETHYL]-4-[METHYLSULFONYL]PHENETHYL)ACETAMIDE;D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-P-(METHYL-SULFONYL)PHENETHYL]ACETAMIDE;8065c.b.;acetamide,2,2-dichloro-n-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl;dextrosulphenidol;thiocymetin CAS: 15318-45-3 MF: C12H15Cl2NO5S MW: 356.22 EINECS: 239-355-3 Chemical Properties Off-White Solid Usage Antimicrobial Usage chelating agent, antiseborrheic Usage Thiamphenicol is an antibiotic. Thiamphenicol is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Thiamphenicol is used particul arly for the treatment of sexually transmitted infections and pelvic inflammatory disease. Usage Thiamphenicol is a semi-synthetic chloramphenicol prepared by total synthesis from thiophenol in which the nitro moiety of chloramphenicol is replaced by a methylsulphone, first synthesised at Sterling Winthrop in 1952. Thiamphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Thiamphenicol acts by binding to the 23S sub-unit of the 50S ribosome inhibiting protein synthesis. Thiamphenicol has been extensively studied with over 800 literature citations.

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