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2015-02-14 |
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81103-11-9 |
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Clarithromycin |
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Offer to Sell |
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Clarithromycin
Synonyms: 6-o-methyl-erythromyci;6-o-methylerythromycina;clathromycin;te-03;TE-031;6-O-METHYLERYTHROMYCIN;6-(4-DIMETHYLAMINO-3-HYDROXY-6-METHYL-OXAN-2-YL)OXY-14-ETHYL-12,13-DIHYDROXY-4-(5-HYDROXY-4-METHOXY-4,6-DIMETHYL-OXAN-2-YL)OXY-7-METHOXY-3,5,7,9,11,13-HEXAMETHYL-1-OXACYCLOTETRADECANE-2,10-DIONE;6-(4-DIMETHYLAMINO-3-HYDROXY-6-METHYLTETRAHYDROPYRAN-2-YL-OXY)-14-ETHYL-12,13-DIHYDROXY-4-(5-HYDROXY)
CAS: 81103-11-9
MF: C38H69NO13
MW: 747.95
Chemical Properties Colourless Crystalline Needles
Usage A semi-synthetic macrolide antibiotic. A derivative of erythromycin
Usage antibacterial
Usage Clarithromycin is a semi-synthetic macrolide antibiotic. Clarithromycin is a derivative of Erythromycin (E650000).
Usage Clarithromycin (6-methoxyerythromycin) is a macrolide antibiotic active against a broad range of Gram positive bacteria. Clarithromycin was designed to enhance acid stability and improve oral bioavailability compared with erythromycin which is highly unstable to acidic conditions, undergoing a series of internal ketalisations between the 9-keto moiety and alcohols at C6 and C11. Omura and colleagues found that protection of the labile 6-OH group by methylation provided a simple but elegant solution. |
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86-027-50755963 |
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