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ÀÔ·ÂÀÏÀÚ: |
2015-02-14 |
À¯È¿ÀÏÀÚ: |
220127-57-1 |
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Imatinib mesylate |
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Offer to Sell |
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Imatinib mesylate
Synonyms: GLIVEC;GLEEVEC;IMATINIB METHANESULFONATE;CGP-57148B;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3)
CAS: 220127-57-1
MF: C30H35N7O4S
MW: 589.71
Chemical Properties Off-White Solid
Usage A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)
Usage Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 ¥ìM, 0.1 ¥ìM and 0.1 ¥ìM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib
Usage Imatinib Mesylate (STI571) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 ¥ìM, 0.1 ¥ìM and 0.1 ¥ìM, respectively.
Usage echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis |
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